Pharmacokinetics of immediate release, extended release, and gastric retentive gabapentin formulations in healthy adults
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منابع مشابه
Comparison of single-dose and multiple-dose pharmacokinetics between two formulations of hydrocodone bitartrate/acetaminophen: immediate-release versus biphasic immediate-release/extended release
OBJECTIVE This study aimed to compare the single-dose and steady-state pharmacokinetics (PK) of biphasic immediate-release (IR)/extended-release (ER) hydrocodone bitartrate (HB)/acetaminophen (APAP) and IR HB/APAP. SETTING The study was conducted in a contract research center. PARTICIPANTS The study included healthy adults. INTERVENTIONS In a three-way crossover study, Study 1, participan...
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The objective of the study was to compare pharmacokinetic and pharmacodynamic parameters of gliclazide after administration of immediate (IR) and modified release (MR) tablets. The experiment included rats with both normoglyceamia and streptozocin (STZ)-induced hyperglyceamia. Several MR formulations were designed and in vitro drug release profile was assessed by a dissolution test. For the fur...
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The aim of this study was to evaluate the difference in pharmacokinetics and pharmacodynamics between extended-release (ER) fluvastatin tablet and its immediate-release (IR) capsule in Chinese healthy subjects. This was an open-label, single/multiple-dose, two-period, two-treatment, crossover, randomized trial with a minimum washout period of 7 days. Twenty healthy male adult subjects were give...
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ژورنال
عنوان ژورنال: Int. Journal of Clinical Pharmacology and Therapeutics
سال: 2018
ISSN: 0946-1965
DOI: 10.5414/cp203166